Myalgia
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| Myalgia | |
|---|---|
| Synonym | Muscle pain |
| Specialty | Rheumatology |
Myalgia, or muscle pain, is a symptom of many diseases and disorders. The most common causes are the overuse or over-stretching of a muscle or group of muscles. Myalgia without a traumatic history is often due to viral infections. Longer-term myalgias may be indicative of a metabolic myopathy, some nutritional deficiencies or chronic fatigue syndrome.
Contents
Causes[edit]
The most common causes of myalgia are overuse, injury or strain. However, myalgia can also be caused by diseases, disorders, medications, or as a response to a vaccination. It is also a sign of acute rejection after heart transplant surgery.
The most common causes are:
- Injury or trauma, including sprains, hematoma
- Overuse: using a muscle too much, too often, including protecting a separate injury
- Chronic tension
Muscle pain occurs with:
- Rhabdomyolysis, associated with:
- Viral
- Compression injury leading to crush syndrome
- Drug-related
- Commonly fibrates and statins
- Occasionally ACE inhibitors, cocaine, and some retro-viral drugs
- Severe potassium deficiency
- Fibromyalgia
- Ehlers-Danlos syndrome
- Auto-immune disorders, including:
- Mixed connective tissue disease
- Systemic lupus erythematosus
- Polymyalgia rheumatica
- Polymyositis
- Dermatomyositis
- Multiple Sclerosis (this is neurologic pain localised to myotome)
- Infections, including:
- Influenza (the flu)
- Lyme disease
- Babesiosis
- Malaria
- Toxoplasmosis
- Dengue fever
- Hemorrhagic fever
- Muscular abscess
- Compartment syndrome
- Polio
- Rocky Mountain spotted fever
- Trichinosis (roundworm)
- Ebola
- Other
Overuse[edit]
Overuse of a muscle is using it too much, too soon and/or too often.[4] Examples are:
Injury[edit]
The most common causes of myalgia by injury are: sprains and strains.[4]
Autoimmune[edit]
Multiple sclerosis (neurologic pain interpreted as muscular), Myalgic Encephalomyelitis (chronic fatigue syndrome), Myositis, Mixed connective tissue disease, Lupus erythematosus, Fibromyalgia syndrome, Familial Mediterranean fever, Polyarteritis nodosa, Devic's disease, Morphea, Sarcoidosis.
Metabolic defect[edit]
Carnitine palmitoyltransferase II deficiency, Conn's syndrome, Adrenal insufficiency, Hyperthyroidism, Hypothyroidism, Diabetes, Hypogonadism, postorgasmic illness syndrome (POIS).[1][2][3]
Other[edit]
Chronic fatigue syndrome a.k.a. Myalgic Encephalomyelitis, Channelopathy, Ehlers Danlos Syndrome, Stickler Syndrome, Hypokalemia, Hypotonia (Low Muscle Tone), Exercise intolerance, Mastocytosis, Peripheral neuropathy, Eosinophilia myalgia syndrome, Barcoo Fever, Herpes, Hemochromatosis a.k.a. Iron Overload Disorder, Delayed onset muscle soreness, AIDS, HIV, Tumor-induced osteomalacia, Hypovitaminosis D, infarction[5]
Withdrawal syndrome from certain drugs[edit]
Sudden cessation of high-dose corticosteroids, opioids, barbiturates, benzodiazepines, caffeine or alcohol can induce myalgia.
Treatment[edit]
When the cause of myalgia is unknown, it should be treated symptomatically. Common treatments include heat, rest, paracetamol, NSAIDs and muscle relaxants.[6]
See also[edit]
References[edit]
- ^ a b Balon R, Segraves RT, eds. (2005). Handbook of Sexual Dysfunction. Taylor & Francis. ISBN 9780824758264.
- ^ a b Wylie KR, ed. (2015). ABC of Sexual Health. John Wiley & Sons. p. 75. ISBN 9781118665565.
- ^ a b "Postorgasmic illness syndrome". Genetic and Rare Diseases Information Center (GARD). National Institutes of Health. 2015. Retrieved 30 July 2015.
- ^ a b MedlinePlus
- ^ Glueck, CharlesJ; Conrad, Brandon (2013). "Severe vitamin D deficiency, myopathy, and rhabdomyolysis". North American Journal of Medical Sciences. 5 (8): 494. doi:10.4103/1947-2714.117325. ISSN 1947-2714.
- ^ Shmerling, Robert H (April 25, 2016). "Approach to the patient with myalgia". UpToDate. Retrieved 2018-05-27. (Subscription required (help)).
External links[edit]
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